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Mechanistically, Beclin-1 binds to solute carrier family 7 member 11 (SLC7A11), a crucial part of system Xc-, inhibiting its action and subsequent ferroptosis through phosphorylating at ser90/93/96 (Song et al., 2018)

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Peptides are small chains of amino acids that can signal your body to release or regulate hormones

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1.1 The first twincretin, Tirzepatide (LY3298176) The chemical formula of TZP is C225H348N48O68, a linear synthetic peptide composed of 39 aminoacids and with a molecular weight of about 48 KDa, which arises from the fusion of aminoacid sequences structurally similar to glucagon, human GIP, GLP-1, exendin-4

Market leader Lilly is developing its own amylin analogue called eloralintide that's already in Phase 3 trials